A red-emitting mitochondria targetable fluorescent probe for detecting viscosity in HeLa, zebrafish, and mice
Gene regulation at scale A landmark study by Loren Pickart (the researcher who originally isolated GHK-Cu) found that GHK-Cu upregulates over 4,000 genes associated with tissue repair and regeneration, while downregulating genes linked to inflammation and cellular senescence
The cells were resuspended in lysis buffer (50 mM Tris-HCl pH 8.0, 500 mM NaCl, 10 mM -mercaptoethanol, 0.5 mM AeBSF, 10 L DNase, 1x Complete protease inhibitor tablet [Roche])
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Biological Inorganic Chemistry , 14(7), 9951000